IGF-1 treatment reduces weight loss and improves outcome in a rat model of cancer cachexia

BACKGROUND: A hallmark symptom of cancer cachexia is the loss of skeletal muscle. This is at least partially due to a deregulation of the growth hormone/IGF-1 axis and a subsequently impaired protein synthesis in skeletal muscle. Here, we investigated the effect of IGF-1 supplementation in a rat mod...

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Detalles Bibliográficos
Autores principales: Schmidt, Katja, von Haehling, Stephan, Doehner, Wolfram, Palus, Sandra, Anker, Stefan D., Springer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117996/
https://www.ncbi.nlm.nih.gov/pubmed/21766056
http://dx.doi.org/10.1007/s13539-011-0029-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117996/
https://www.ncbi.nlm.nih.gov/pubmed/21766056
http://dx.doi.org/10.1007/s13539-011-0029-3

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