Onconase Mediated NFKβ Down-Regulation in Malignant Pleural Mesothelioma

PURPOSE: Treatment of malignant pleural mesothelioma (MPM) with Ranpirnase (Onconase) results in disruption of protein translation and cell apoptosis. We hypothesize that Onconase acts via down regulation of nuclear factor kappa B (NFKβ) by specific microRNAs (miRNA) and that interference of this pa...

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Detalles Bibliográficos
Autores principales: Goparaju, Chandra M., Blasberg, Justin D., Volinia, Stefano, Palatini, Jeff, Ivanov, Sergey, Donington, Jessica S., Croce, Carlo, Carbone, Michele, Yang, Haining, Pass, Harvey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118086/
https://www.ncbi.nlm.nih.gov/pubmed/21317924
http://dx.doi.org/10.1038/onc.2010.643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118086/
https://www.ncbi.nlm.nih.gov/pubmed/21317924
http://dx.doi.org/10.1038/onc.2010.643

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