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Combining an Evolution-guided Clustering Algorithm and Haplotype-based LRT in Family Association Studies

BACKGROUND: With the completion of the international HapMap project, many studies have been conducted to investigate the association between complex diseases and haplotype variants. Such haplotype-based association studies, however, often face two difficulties; one is the large number of haplotype c...

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Detalles Bibliográficos
Autores principales: Lee, Mei-Hsien, Tzeng, Jung-Ying, Huang, Su-Yun, Hsiao, Chuhsing Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118131/
https://www.ncbi.nlm.nih.gov/pubmed/21592403
http://dx.doi.org/10.1186/1471-2156-12-48