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Combining an Evolution-guided Clustering Algorithm and Haplotype-based LRT in Family Association Studies
BACKGROUND: With the completion of the international HapMap project, many studies have been conducted to investigate the association between complex diseases and haplotype variants. Such haplotype-based association studies, however, often face two difficulties; one is the large number of haplotype c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118131/ https://www.ncbi.nlm.nih.gov/pubmed/21592403 http://dx.doi.org/10.1186/1471-2156-12-48 |