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Non-endothelial endothelin counteracts hypoxic vasodilation in porcine large coronary arteries
BACKGROUND: The systemic vascular response to hypoxia is vasodilation. However, reports suggest that the potent vasoconstrictor endothelin-1 (ET-1) is released from the vasculature during hypoxia. ET-1 is reported to augment superoxide anion generation and may counteract nitric oxide (NO) vasodilati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118136/ https://www.ncbi.nlm.nih.gov/pubmed/21575165 http://dx.doi.org/10.1186/1472-6793-11-8 |