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Non-endothelial endothelin counteracts hypoxic vasodilation in porcine large coronary arteries

BACKGROUND: The systemic vascular response to hypoxia is vasodilation. However, reports suggest that the potent vasoconstrictor endothelin-1 (ET-1) is released from the vasculature during hypoxia. ET-1 is reported to augment superoxide anion generation and may counteract nitric oxide (NO) vasodilati...

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Detalles Bibliográficos
Autores principales:	Hedegaard, Elise R, Stankevicius, Edgaras, Simonsen, Ulf, Fröbert, Ole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118136/ https://www.ncbi.nlm.nih.gov/pubmed/21575165 http://dx.doi.org/10.1186/1472-6793-11-8

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