Cargando…

Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models

BACKGROUND: The binding of EGFR and its ligands leads to autophosphorylation of receptor tyrosine kinase as well as subsequent activation of signal transduction pathways that are involved in regulating cellular proliferation, differentiation, and survival. An EGFR inhibitor, cetuximab binds to EGFR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsuo, Teppei, Nishizuka, Satoshi S, Ishida, Kazushige, Iwaya, Takeshi, Ikeda, Miyuki, Wakabayashi, Go
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118158/ https://www.ncbi.nlm.nih.gov/pubmed/21554739 http://dx.doi.org/10.1186/1756-0500-4-140

Ejemplares similares

Evaluation of chemosensitivity prediction using quantitative dose–response curve classification for highly advanced/relapsed gastric cancer
por: Matsuo, Teppei, et al.
Publicado: (2013)

A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines
por: Endo, Fumitaka, et al.
Publicado: (2014)

Molecular Marker Identification for Relapse Prediction in 5-FU-Based Adjuvant Chemotherapy in Gastric and Colorectal Cancers
por: Ishida, Kazushige, et al.
Publicado: (2012)

Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel
por: Sato, Kei A., et al.
Publicado: (2016)

α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15
por: Kume, Kohei, et al.
Publicado: (2016)

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer
por: Klinghammer, Konrad, et al.
Publicado: (2020)

MAD‐related Genes on 18q21.1, Smad2 and Smad4, Are Altered Infrequently in Esophageal Squamous Cell Carcinoma
por: Maesawa, Chihaya, et al.
Publicado: (1997)

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts
por: TSUKIHARA, HIROSHI, et al.
Publicado: (2015)

Cetuximab delivery and antitumor effects are enhanced by mild hyperthermia in a xenograft mouse model of pancreatic cancer
por: Miyamoto, Ryoichi, et al.
Publicado: (2016)

Cetuximab intensifies the ADCC activity of adoptive NK cells in a nude mouse colorectal cancer xenograft model
por: Chen, Shanshan, et al.
Publicado: (2016)

Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-β-induced EMT in human lung adenocarcinoma
por: Satoh, Kotone, et al.
Publicado: (2022)

High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
por: Sommariva, Michele, et al.
Publicado: (2013)

Efficacy of a combination therapy targeting CDK4/6 and autophagy in a mouse xenograft model of t(8;21) acute myeloid leukemia
por: Matsuo, Hidemasa, et al.
Publicado: (2021)

PTEN status in advanced colorectal cancer treated with cetuximab
por: Negri, F V, et al.
Publicado: (2010)

Near-Infrared Fluorescence Imaging of EGFR-Overexpressing Tumors in the Mouse Xenograft Model Using scFv-IRDye800CW and Cetuximab-IRDye800CW
por: Amini, Abolfazl, et al.
Publicado: (2022)

Severe skin reaction secondary to concomitant radiotherapy plus cetuximab
por: Berger, Bernhard, et al.
Publicado: (2008)

Pretargeting of internalizing trastuzumab and cetuximab with a (18)F-tetrazine tracer in xenograft models
por: Keinänen, Outi, et al.
Publicado: (2017)

Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma
por: Kogo, Ryunosuke, et al.
Publicado: (2022)

Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [(18)F]FDG, [(18)F]FLT, and [(64)Cu]NODAGA-cetuximab small animal PET
por: Honndorf, Valerie S., et al.
Publicado: (2016)

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent
por: Cheng, Yinwen, et al.
Publicado: (2021)

Immunohistochemical analyses of the kinetics and distribution of macrophages in the developing rat kidney
por: Matsuyama, Satoshi, et al.
Publicado: (2018)

Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil
por: Ishida, Kaoru, et al.
Publicado: (2017)

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab
por: He, Xuzhi, et al.
Publicado: (2018)

Inactivation of the E‐Cadherin Gene in Primary Gastric Carcinomas and Gastric Carcinoma Cell Lines
por: Tamura, Gen, et al.
Publicado: (1996)

Analysis of the DPC4 Gene in Gastric Carcinoma
por: Nishizuka, Satoshi, et al.
Publicado: (1997)

Cetuximab in the treatment of head and neck cancer: preliminary results outside clinical trials
por: Dequanter, Didier, et al.
Publicado: (2010)

Gene delivery in a mouse xenograft of a retargeted retrovirus to a solid 143B osteosarcoma
por: Zhang, Xia, et al.
Publicado: (2013)

Applications of patient-derived tumor xenograft models and tumor organoids
por: Yoshida, Go J.
Publicado: (2020)

Effect of ultrasound on the kinetics of anti-solvent crystallization of sucrose
por: Zhong, Xuwei, et al.
Publicado: (2021)

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature
por: Guo, Sheng, et al.
Publicado: (2016)

Lasting response by vertical inhibition with cetuximab and trametinib in KRAS‐mutated colorectal cancer patient‐derived xenografts
por: Reissig, Timm M., et al.
Publicado: (2023)

The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines
por: Boeckx, Carolien, et al.
Publicado: (2015)

Defucosylated Mouse–Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors
por: Li, Guanjie, et al.
Publicado: (2021)

Scanning Acoustic Microscopy—A Novel Noninvasive Method to Determine Tumor Interstitial Fluid Pressure in a Xenograft Tumor Model()
por: Hofmann, Matthias, et al.
Publicado: (2016)

Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in colorectal cancer cell
por: Yang, Xiaohui, et al.
Publicado: (2020)

Dasatinib worsens the effect of cetuximab in combination with fractionated radiotherapy in FaDu- and A431-derived xenografted tumours
por: Baro, M, et al.
Publicado: (2014)

Expression of the chemokine CXCL14 and cetuximab-dependent tumour suppression in head and neck squamous cell carcinoma
por: Kondo, T, et al.
Publicado: (2016)

Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model
por: Durante, Sandra, et al.
Publicado: (2014)

Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts
por: Coutinho de Souza, Patricia, et al.
Publicado: (2015)

Anti-tumor Efficacy of CD19 CAR-T in a Raji B Cell Xenografted Mouse Model
por: Xiao, Qian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bb3q2tf2m6a3ah10gjejgtsgn2