A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells

BACKGROUND: Methuosis is a unique form of non-apoptotic cell death triggered by alterations in the trafficking of clathrin-independent endosomes, ultimately leading to extreme vacuolization and rupture of the cell. RESULTS: Here we describe a novel chalcone-like molecule, 3-(2-methyl-1H- indol-3-yl)...

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Detalles Bibliográficos
Autores principales: Overmeyer, Jean H, Young, Ashley M, Bhanot, Haymanti, Maltese, William A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118192/
https://www.ncbi.nlm.nih.gov/pubmed/21639944
http://dx.doi.org/10.1186/1476-4598-10-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118192/
https://www.ncbi.nlm.nih.gov/pubmed/21639944
http://dx.doi.org/10.1186/1476-4598-10-69

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