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A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells

BACKGROUND: Methuosis is a unique form of non-apoptotic cell death triggered by alterations in the trafficking of clathrin-independent endosomes, ultimately leading to extreme vacuolization and rupture of the cell. RESULTS: Here we describe a novel chalcone-like molecule, 3-(2-methyl-1H- indol-3-yl)...

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Detalles Bibliográficos
Autores principales:	Overmeyer, Jean H, Young, Ashley M, Bhanot, Haymanti, Maltese, William A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118192/ https://www.ncbi.nlm.nih.gov/pubmed/21639944 http://dx.doi.org/10.1186/1476-4598-10-69

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