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Alternative statistical methods for estimating efficacy of interferon beta-1b for multiple sclerosis clinical trials

BACKGROUND: In the randomized study of interferon beta-1b (IFN beta-1b) for multiple sclerosis (MS), it has usually been evaluated the simple annual relapse rate as the study endpoint. This study aimed to investigate the performance of various regression models using information regarding the time t...

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Detalles Bibliográficos
Autores principales: Mieno, Makiko N, Yamaguchi, Takuhiro, Ohashi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118202/
https://www.ncbi.nlm.nih.gov/pubmed/21612661
http://dx.doi.org/10.1186/1471-2288-11-80