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Alternative statistical methods for estimating efficacy of interferon beta-1b for multiple sclerosis clinical trials
BACKGROUND: In the randomized study of interferon beta-1b (IFN beta-1b) for multiple sclerosis (MS), it has usually been evaluated the simple annual relapse rate as the study endpoint. This study aimed to investigate the performance of various regression models using information regarding the time t...
Autores principales: | Mieno, Makiko N, Yamaguchi, Takuhiro, Ohashi, Yasuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118202/ https://www.ncbi.nlm.nih.gov/pubmed/21612661 http://dx.doi.org/10.1186/1471-2288-11-80 |
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