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Analysis of in vitro bioactivity data extracted from drug discovery literature and patents: Ranking 1654 human protein targets by assayed compounds and molecular scaffolds

BACKGROUND: Since the classic Hopkins and Groom druggable genome review in 2002, there have been a number of publications updating both the hypothetical and successful human drug target statistics. However, listings of research targets that define the area between these two extremes are sparse becau...

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Detalles Bibliográficos
Autores principales: Southan, Christopher, Boppana, Kiran, Jagarlapudi, Sarma ARP, Muresan, Sorel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118229/
https://www.ncbi.nlm.nih.gov/pubmed/21569515
http://dx.doi.org/10.1186/1758-2946-3-14