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Analysis of in vitro bioactivity data extracted from drug discovery literature and patents: Ranking 1654 human protein targets by assayed compounds and molecular scaffolds
BACKGROUND: Since the classic Hopkins and Groom druggable genome review in 2002, there have been a number of publications updating both the hypothetical and successful human drug target statistics. However, listings of research targets that define the area between these two extremes are sparse becau...
Autores principales: | Southan, Christopher, Boppana, Kiran, Jagarlapudi, Sarma ARP, Muresan, Sorel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118229/ https://www.ncbi.nlm.nih.gov/pubmed/21569515 http://dx.doi.org/10.1186/1758-2946-3-14 |
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