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Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice

BACKGROUND: Cerebral malaria (CM) is a lethal complication of Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM is associated with marked brain inflammation, increased expression of endothelial cell adhesion molecules and leukocyte and platelet accumulation in b...

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Detalles Bibliográficos
Autores principales: Zanini, Graziela M, Cabrales, Pedro, Barkho, Wisam, Frangos, John A, Carvalho, Leonardo JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118350/
https://www.ncbi.nlm.nih.gov/pubmed/21649904
http://dx.doi.org/10.1186/1742-2094-8-66