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Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury

BACKGROUND: Genotoxic stress, such as by exposure to bromodeoxyuridine (BrdU) and cigarette smoke, induces premature cell senescence. Recent evidence indicates that cellular senescence of various types of cells is accelerated in COPD patients. However, whether the senescence of airway epithelial cel...

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Detalles Bibliográficos
Autores principales: Zhou, Fang, Onizawa, Shigemitsu, Nagai, Atsushi, Aoshiba, Kazutetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118351/
https://www.ncbi.nlm.nih.gov/pubmed/21663649
http://dx.doi.org/10.1186/1465-9921-12-78