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A computational model of the hypothalamic - pituitary - gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone

BACKGROUND: Endocrine disrupting chemicals (e.g., estrogens, androgens and their mimics) are known to affect reproduction in fish. 17α-ethynylestradiol is a synthetic estrogen used in birth control pills. 17β-trenbolone is a relatively stable metabolite of trenbolone acetate, a synthetic androgen us...

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Detalles Bibliográficos
Autores principales: Li, Zhenhong, Kroll, Kevin J, Jensen, Kathleen M, Villeneuve, Daniel L, Ankley, Gerald T, Brian, Jayne V, Sepúlveda, María S, Orlando, Edward F, Lazorchak, James M, Kostich, Mitchell, Armstrong, Brandon, Denslow, Nancy D, Watanabe, Karen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118352/
https://www.ncbi.nlm.nih.gov/pubmed/21545743
http://dx.doi.org/10.1186/1752-0509-5-63