Model-Integrated Estimation of Normal Tissue Contamination for Cancer SNP Allelic Copy Number Data

SNP allelic copy number data provides intensity measurements for the two different alleles separately. We present a method that estimates the number of copies of each allele at each SNP position, using a continuous-index hidden Markov model. The method is especially suited for cancer data, since it...

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Detalles Bibliográficos
Autores principales: Stjernqvist, Susann, Rydén, Tobias, Greenman, Chris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118450/
https://www.ncbi.nlm.nih.gov/pubmed/21695067
http://dx.doi.org/10.4137/CIN.S6873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118450/
https://www.ncbi.nlm.nih.gov/pubmed/21695067
http://dx.doi.org/10.4137/CIN.S6873

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