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Model-Integrated Estimation of Normal Tissue Contamination for Cancer SNP Allelic Copy Number Data
SNP allelic copy number data provides intensity measurements for the two different alleles separately. We present a method that estimates the number of copies of each allele at each SNP position, using a continuous-index hidden Markov model. The method is especially suited for cancer data, since it...
Autores principales: | Stjernqvist, Susann, Rydén, Tobias, Greenman, Chris D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118450/ https://www.ncbi.nlm.nih.gov/pubmed/21695067 http://dx.doi.org/10.4137/CIN.S6873 |
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