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Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease

Imbalance in the activity of striatal direct and indirect pathway neurons contributes to motor disturbances in several neurodegenerative diseases. In Huntington's disease (HD), indirect pathway [dopamine (DA) D2 receptor-expressing] medium-sized spiny neurons (MSNs) are believed to show earlier...

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Detalles Bibliográficos
Autores principales: André, Véronique M., Fisher, Yvette E., Levine, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118454/
https://www.ncbi.nlm.nih.gov/pubmed/21720523
http://dx.doi.org/10.3389/fnsys.2011.00046