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Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease
Imbalance in the activity of striatal direct and indirect pathway neurons contributes to motor disturbances in several neurodegenerative diseases. In Huntington's disease (HD), indirect pathway [dopamine (DA) D2 receptor-expressing] medium-sized spiny neurons (MSNs) are believed to show earlier...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118454/ https://www.ncbi.nlm.nih.gov/pubmed/21720523 http://dx.doi.org/10.3389/fnsys.2011.00046 |