Activation of the GLP-1 Receptor Signalling Pathway: A Relevant Strategy to Repair a Deficient Beta-Cell Mass

Recent preclinical studies in rodent models of diabetes suggest that exogenous GLP-1R agonists and DPP-4 inhibitors have the ability to increase islet mass and preserve beta-cell function, by immediate reactivation of beta-cell glucose competence, as well as enhanced beta-cell proliferation and neog...

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Detalles Bibliográficos
Autores principales: Portha, Bernard, Tourrel-Cuzin, Cécile, Movassat, Jamileh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118608/
https://www.ncbi.nlm.nih.gov/pubmed/21716694
http://dx.doi.org/10.1155/2011/376509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118608/
https://www.ncbi.nlm.nih.gov/pubmed/21716694
http://dx.doi.org/10.1155/2011/376509

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