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Optimizing supercritical antisolvent process parameters to minimize the particle size of paracetamol nanoencapsulated in L-polylactide

BACKGROUND: The aim of this study was to optimize the different process parameters including pressure, temperature, and polymer concentration, to produce fine small spherical particles with a narrow particle size distribution using a supercritical antisolvent method for drug encapsulation. The inter...

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Detalles Bibliográficos
Autores principales: Kalani, Mahshid, Yunus, Robiah, Abdullah, Norhafizah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118683/
https://www.ncbi.nlm.nih.gov/pubmed/21698077
http://dx.doi.org/10.2147/IJN.S18979