Toxicity Testing in the 21(st) Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways

The approaches to quantitatively assessing the health risks of chemical exposure have not changed appreciably in the past 50 to 80 years, the focus remaining on high-dose studies that measure adverse outcomes in homogeneous animal populations. This expensive, low-throughput approach relies on conser...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Sudin, Zhang, Qiang, Carmichael, Paul L., Boekelheide, Kim, Andersen, Melvin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118802/
https://www.ncbi.nlm.nih.gov/pubmed/21701582
http://dx.doi.org/10.1371/journal.pone.0020887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118802/
https://www.ncbi.nlm.nih.gov/pubmed/21701582
http://dx.doi.org/10.1371/journal.pone.0020887

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