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Toxicity Testing in the 21(st) Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways
The approaches to quantitatively assessing the health risks of chemical exposure have not changed appreciably in the past 50 to 80 years, the focus remaining on high-dose studies that measure adverse outcomes in homogeneous animal populations. This expensive, low-throughput approach relies on conser...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118802/ https://www.ncbi.nlm.nih.gov/pubmed/21701582 http://dx.doi.org/10.1371/journal.pone.0020887 |