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Extracellular Matrix-associated Cytokines Regulate CD4(+) Effector T-cell Responses in Human Intestinal Mucosa

Extracellular matrix (stroma) regulation of mucosal T-cell function is incompletely understood. Here we uncovered a role for intestinal stromal products in the innate regulation of effector T-cells. Stroma-conditioned media (S-CM) derived from normal human intestinal stroma (TGF-β(hi)/IL-6(lo)/IL-1β...

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Detalles Bibliográficos
Autores principales: Huff, Kayci R., Akhtar, Lisa Nowoslawski, Fox, Anna L., Cannon, Jamie A., Smith, Phillip D., Smythies, Lesley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118864/
https://www.ncbi.nlm.nih.gov/pubmed/21228771
http://dx.doi.org/10.1038/mi.2010.86