Cargando…
Urothelial antigen-specific CD4(+) T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8(+) T cells
The role of CD4(+) T cells in bladder autoimmune inflammation has not been identified due to the lack of a proper animal model. We investigated CD4(+) T cell responses to bladder urothelial ovalbumin (OVA), a model self-antigen (Ag), in transgenic URO-OVA mice. The expression of bladder urothelial O...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118865/ https://www.ncbi.nlm.nih.gov/pubmed/21270773 http://dx.doi.org/10.1038/mi.2010.90 |