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The synthetic peptide P111-136 derived from the C-terminal domain of heparin affin regulatory peptide inhibits tumour growth of prostate cancer PC-3 cells

BACKGROUND: Heparin affin regulatory peptide (HARP), also called pleiotrophin, is a heparin-binding, secreted factor that is overexpressed in several tumours and associated to tumour growth, angiogenesis and metastasis. The C-terminus part of HARP composed of amino acids 111 to 136 is particularly i...

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Detalles Bibliográficos
Autores principales: Hamma-Kourbali, Yamina, Bermek, Oya, Bernard-Pierrot, Isabelle, Karaky, Racha, Martel-Renoir, Dominique, Frechault, Sophie, Courty, José, Delbé, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118947/
https://www.ncbi.nlm.nih.gov/pubmed/21624116
http://dx.doi.org/10.1186/1471-2407-11-212