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The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

BACKGROUND: Arachidonic acid (AA) is a long-chain omega-6 polyunsaturated fatty acid (PUFA) synthesized from the precursor dihomo-gamma-linolenic acid (DGLA) that plays a vital role in immunity and inflammation. Variants in the Fatty Acid Desaturase (FADS) family of genes on chromosome 11q have been...

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Detalles Bibliográficos
Autores principales: Mathias, Rasika A, Sergeant, Susan, Ruczinski, Ingo, Torgerson, Dara G, Hugenschmidt, Christina E, Kubala, Meghan, Vaidya, Dhananjay, Suktitipat, Bhoom, Ziegler, Julie T, Ivester, Priscilla, Case, Douglas, Yanek, Lisa R, Freedman, Barry I, Rudock, Megan E, Barnes, Kathleen C, Langefeld, Carl D, Becker, Lewis C, Bowden, Donald W, Becker, Diane M, Chilton, Floyd H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118962/
https://www.ncbi.nlm.nih.gov/pubmed/21599946
http://dx.doi.org/10.1186/1471-2156-12-50