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Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo
BACKGROUND: The human coagulation trigger tissue factor (TF) is overexpressed in several types of cancer and involved in tumor growth, vascularization, and metastasis. To explore the role of TF in biological processes of lung adenocarcinoma, we used RNA interference (RNAi) technology to silence TF i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118969/ https://www.ncbi.nlm.nih.gov/pubmed/21619686 http://dx.doi.org/10.1186/1756-9966-30-63 |