High-Resolution X-Ray Structure of the Trimeric Scar/WAVE-Complex Precursor Brk1

The Scar/WAVE-complex links upstream Rho-GTPase signaling to the activation of the conserved Arp2/3-complex. Scar/WAVE-induced and Arp2/3-complex-mediated actin nucleation is crucial for actin assembly in protruding lamellipodia to drive cell migration. The heteropentameric Scar/WAVE-complex is comp...

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Detalles Bibliográficos
Autores principales: Linkner, Joern, Witte, Gregor, Stradal, Theresia, Curth, Ute, Faix, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119050/
https://www.ncbi.nlm.nih.gov/pubmed/21701600
http://dx.doi.org/10.1371/journal.pone.0021327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119050/
https://www.ncbi.nlm.nih.gov/pubmed/21701600
http://dx.doi.org/10.1371/journal.pone.0021327

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