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Pharmacological Blockade of Serotonin 5-HT(7) Receptor Reverses Working Memory Deficits in Rats by Normalizing Cortical Glutamate Neurotransmission

The role of 5-HT(7) receptor has been demonstrated in various animal models of mood disorders; however its function in cognition remains largely speculative. This study evaluates the effects of SB-269970, a selective 5-HT(7) antagonist, in a translational model of working memory deficit and investig...

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Detalles Bibliográficos
Autores principales:	Bonaventure, Pascal, Aluisio, Leah, Shoblock, James, Boggs, Jamin D., Fraser, Ian C., Lord, Brian, Lovenberg, Timothy W., Galici, Ruggero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119073/ https://www.ncbi.nlm.nih.gov/pubmed/21701689 http://dx.doi.org/10.1371/journal.pone.0020210

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