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A Cascade of Protein Kinase C Isozymes Promotes Cytoskeletal Polarization in T Cells

Polarization of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting cell is driven by the accumulation of diacylglycerol at the immunological synapse (IS). The mechanisms that couple diacylglycerol to the MTOC are not known. Using single-cell photoactivation of the T cell r...

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Detalles Bibliográficos
Autores principales: Quann, Emily J., Liu, Xin, Altan-Bonnet, Grégoire, Huse, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119370/
https://www.ncbi.nlm.nih.gov/pubmed/21602810
http://dx.doi.org/10.1038/ni.2033