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A Cascade of Protein Kinase C Isozymes Promotes Cytoskeletal Polarization in T Cells
Polarization of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting cell is driven by the accumulation of diacylglycerol at the immunological synapse (IS). The mechanisms that couple diacylglycerol to the MTOC are not known. Using single-cell photoactivation of the T cell r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119370/ https://www.ncbi.nlm.nih.gov/pubmed/21602810 http://dx.doi.org/10.1038/ni.2033 |