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Host Kinase Activity is Required for Coxiella burnetii Parasitophorous Vacuole Formation

Coxiella burnetii is the etiologic agent of human Q fever and targets alveolar phagocytic cells in vivo wherein the pathogen generates a phagolysosome-like parasitophorous vacuole (PV) for replication. C. burnetii displays a prolonged growth cycle, making PV maintenance critical for bacterial surviv...

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Detalles Bibliográficos
Autores principales: Hussain, S. Kauser, Broederdorf, Laura J., Sharma, Uma M., Voth, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119423/
https://www.ncbi.nlm.nih.gov/pubmed/21772829
http://dx.doi.org/10.3389/fmicb.2010.00137