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A functional type I interferon pathway drives resistance to cornea herpes simplex virus type 1 infection by recruitment of leukocytes()

Type I interferons are critical antiviral cytokines produced following herpes simplex virus type-1 (HSV-1) infection that act to inhibit viral spread. In the present study, we identify HSV-infected and adjacent uninfected corneal epithelial cells as the source of interferon-α. We also report mice de...

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Detalles Bibliográficos
Autores principales: Conrady, Christopher D., Jones, Heather, Zheng, Min, Carr, Daniel J.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119485/
https://www.ncbi.nlm.nih.gov/pubmed/21709805
http://dx.doi.org/10.1016/S1674-8301(11)60014-6