Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases

The ErbB/EGFR/HER family of kinases consists of four homologous receptor tyrosine kinases which are important regulatory elements in many cellular processes, including cell proliferation, differentiation, and migration. Somatic mutations in, or over-expression of, the ErbB family is found in many ca...

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Detalles Bibliográficos
Autores principales: Shih, Andrew J., Telesco, Shannon E., Radhakrishnan, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119571/
https://www.ncbi.nlm.nih.gov/pubmed/21701703
http://dx.doi.org/10.3390/cancers3011195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119571/
https://www.ncbi.nlm.nih.gov/pubmed/21701703
http://dx.doi.org/10.3390/cancers3011195

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