Cargando…

Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display

Highly pathogenic H5N1 avian influenza viruses pose a debilitating pandemic threat. Thus, understanding mechanisms of antibody-mediated viral inhibition and neutralization escape is critical. Here, a robust yeast display system for fine epitope mapping of viral surface hemagglutinin (HA)-specific an...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Thomas, Sui, Jianhua, Bennett, Andrew S., Liddington, Robert C., Donis, Ruben O., Zhu, Quan, Marasco, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. Published by Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119598/
https://www.ncbi.nlm.nih.gov/pubmed/21569761
http://dx.doi.org/10.1016/j.bbrc.2011.04.139