Modulation of Myocardial Mitochondrial Mechanisms during Severe Polymicrobial Sepsis in the Rat

BACKGROUND: We tested the hypothesis that 5-Hydroxydecanoic acid (5HD), a putative mitoK(ATP) channel blocker, will reverse sepsis-induced cardiodynamic and adult rat ventricular myocyte (ARVM) contractile dysfunction, restore mitochondrial membrane permeability alterations and improve survival. MET...

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Detalles Bibliográficos
Autores principales: Chopra, Mani, Golden, Honey B., Mullapudi, Srinivas, Dowhan, William, Dostal, David E., Sharma, Avadhesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119671/
https://www.ncbi.nlm.nih.gov/pubmed/21712982
http://dx.doi.org/10.1371/journal.pone.0021285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119671/
https://www.ncbi.nlm.nih.gov/pubmed/21712982
http://dx.doi.org/10.1371/journal.pone.0021285

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