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Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate—a validated assay for the clinic

The neuraminidase inhibitor oseltamivir (Tamiflu®) is currently the first-line therapy for patients with influenza virus infection. Common analysis of the prodrug and its active metabolite oseltamivircarboxylate is determined via extraction from plasma. Compared with these assays, dried blood spot (...

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Detalles Bibliográficos
Autores principales: Hooff, Gero P., Meesters, Roland J. W., van Kampen, Jeroen J. A., van Huizen, Nick A., Koch, Birgit, Al Hadithy, Asmar F. Y., van Gelder, Teun, Osterhaus, Albert D. M. E., Gruters, Rob A., Luider, Theo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119796/
https://www.ncbi.nlm.nih.gov/pubmed/21537911
http://dx.doi.org/10.1007/s00216-011-5050-z