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Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate—a validated assay for the clinic
The neuraminidase inhibitor oseltamivir (Tamiflu®) is currently the first-line therapy for patients with influenza virus infection. Common analysis of the prodrug and its active metabolite oseltamivircarboxylate is determined via extraction from plasma. Compared with these assays, dried blood spot (...
Autores principales: | Hooff, Gero P., Meesters, Roland J. W., van Kampen, Jeroen J. A., van Huizen, Nick A., Koch, Birgit, Al Hadithy, Asmar F. Y., van Gelder, Teun, Osterhaus, Albert D. M. E., Gruters, Rob A., Luider, Theo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119796/ https://www.ncbi.nlm.nih.gov/pubmed/21537911 http://dx.doi.org/10.1007/s00216-011-5050-z |
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