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Temporal Expression of Mutant LRRK2 in Adult Rats Impairs Dopamine Reuptake

Parkinson's disease (PD) results from progressive degeneration of dopaminergic neurons. Most PD cases are sporadic, but some have pathogenic mutation in the individual genes. Mutation of the leucine-rich repeat kinase-2 (LRRK2) gene is associated with familial and sporadic PD, as exemplified by...

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Detalles Bibliográficos
Autores principales: Zhou, Hongxia, Huang, Cao, Tong, Jianbin, Hong, Weimin C, Liu, Yong-Jian, Xia, Xu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119847/
https://www.ncbi.nlm.nih.gov/pubmed/21698001