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Overexpression of human virus surface glycoprotein precursors induces cytosolic unfolded protein response in Saccharomyces cerevisiae

BACKGROUND: The expression of human virus surface proteins, as well as other mammalian glycoproteins, is much more efficient in cells of higher eukaryotes rather than yeasts. The limitations to high-level expression of active viral surface glycoproteins in yeast are not well understood. To identify...

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Detalles Bibliográficos
Autores principales: Čiplys, Evaldas, Samuel, Dhanraj, Juozapaitis, Mindaugas, Sasnauskas, Kęstutis, Slibinskas, Rimantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120639/
https://www.ncbi.nlm.nih.gov/pubmed/21595909
http://dx.doi.org/10.1186/1475-2859-10-37