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Overexpression of human virus surface glycoprotein precursors induces cytosolic unfolded protein response in Saccharomyces cerevisiae
BACKGROUND: The expression of human virus surface proteins, as well as other mammalian glycoproteins, is much more efficient in cells of higher eukaryotes rather than yeasts. The limitations to high-level expression of active viral surface glycoproteins in yeast are not well understood. To identify...
Autores principales: | Čiplys, Evaldas, Samuel, Dhanraj, Juozapaitis, Mindaugas, Sasnauskas, Kęstutis, Slibinskas, Rimantas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120639/ https://www.ncbi.nlm.nih.gov/pubmed/21595909 http://dx.doi.org/10.1186/1475-2859-10-37 |
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