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Impact of accessory gene regulator (agr) dysfunction on vancomycin pharmacodynamics among Canadian community and health-care associated methicillin-resistant Staphylococcus aureus

BACKGROUND: The accessory gene regulator (agr) is a quorum sensing cluster of genes which control colonization and virulence in Staphylococcus aureus. We evaluated agr function in community- (CA) and healthcare-associated (HA) MRSA, to compare the pharmacodynamics and bactericidal activity of vancom...

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Detalles Bibliográficos
Autores principales: Tsuji, Brian T, MacLean, Robert D, Dresser, Linda D, McGavin, Martin J, Simor, Andrew E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120648/
https://www.ncbi.nlm.nih.gov/pubmed/21599878
http://dx.doi.org/10.1186/1476-0711-10-20