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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice
BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120668/ https://www.ncbi.nlm.nih.gov/pubmed/21595935 http://dx.doi.org/10.1186/1465-9921-12-64 |