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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice

BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...

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Detalles Bibliográficos
Autores principales:	Hulo, Sébastien, Tiesset, Hélène, Lancel, Steve, Viollet, Benoit, Sobaszek, Annie, Nevière, Rémi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120668/ https://www.ncbi.nlm.nih.gov/pubmed/21595935 http://dx.doi.org/10.1186/1465-9921-12-64

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