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DJ-1 can inhibit microtubule associated protein 1 B formed aggregates

BACKGROUND: Abnormal accumulation and aggregation of microtubule associated proteins (MAPs) plays an important role in the pathogenesis of neurodegenerative diseases. Loss-of-function mutation of DJ-1/Park7 can cause early onset of PD. DJ-1, a molecular chaperone, can inhibit α-synuclein aggregation...

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Detalles Bibliográficos
Autores principales: Wang, Zhiquan, Zhang, Yu, Zhang, Shi, Guo, Qianqian, Tan, Yuyan, Wang, Xinyi, Xiong, Ran, Ding, Jianqing, Chen, Shengdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120713/
https://www.ncbi.nlm.nih.gov/pubmed/21645326
http://dx.doi.org/10.1186/1750-1326-6-38