Pyrosequencing, a method approved to detect the two major EGFR mutations for anti EGFR therapy in NSCLC

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) mutations, especially in-frame deletions in exon 19 (ΔLRE) and a point mutation in exon 21 (L858R) predict gefitinib sensitivity in patients with non-small cell lung cancer. Several methods are currently described for their detection but the gold s...

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Detalles Bibliográficos
Autores principales: Dufort, Sandrine, Richard, Marie-Jeanne, Lantuejoul, Sylvie, de Fraipont, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120717/
https://www.ncbi.nlm.nih.gov/pubmed/21575212
http://dx.doi.org/10.1186/1756-9966-30-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120717/
https://www.ncbi.nlm.nih.gov/pubmed/21575212
http://dx.doi.org/10.1186/1756-9966-30-57

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