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Pyrosequencing, a method approved to detect the two major EGFR mutations for anti EGFR therapy in NSCLC
BACKGROUND: Epidermal Growth Factor Receptor (EGFR) mutations, especially in-frame deletions in exon 19 (ΔLRE) and a point mutation in exon 21 (L858R) predict gefitinib sensitivity in patients with non-small cell lung cancer. Several methods are currently described for their detection but the gold s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120717/ https://www.ncbi.nlm.nih.gov/pubmed/21575212 http://dx.doi.org/10.1186/1756-9966-30-57 |