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Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice

BACKGROUND: Erythropoietin (EPO) and its receptor (EPOR) are expressed in the developing brain and their transcription is upregulated in adult neurons and glia upon injury or neurodegeneration. We have shown neuroprotective effects and improved cognition in patients with neuropsychiatric diseases tr...

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Detalles Bibliográficos
Autores principales: Sargin, Derya, El-Kordi, Ahmed, Agarwal, Amit, Müller, Michael, Wojcik, Sonja M, Hassouna, Imam, Sperling, Swetlana, Nave, Klaus-Armin, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120735/
https://www.ncbi.nlm.nih.gov/pubmed/21527022
http://dx.doi.org/10.1186/1741-7007-9-27