Cargando…
The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression
BACKGROUND: Infection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell carcinomas (SCCs) of the anogenital tract and a subset of oropharyngeal carcinomas. Such lesions, including pre-invasive precursors, frequently show multipolar mitoses and an...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120798/ https://www.ncbi.nlm.nih.gov/pubmed/21609466 http://dx.doi.org/10.1186/1476-4598-10-61 |